Preliminary experiments show conolidine might inhibit specific ion channels, decreasing neuronal excitability and limiting ache signals. This system is especially related in neuropathic ache, wherever irregular signaling leads to persistent irritation. In addition, conolidine seems to affect G protein-coupled receptor (GPCR) pathways integral to suffering notion. Computational docking... https://johnw802wgu1.wikiusnews.com/user