Pentobarbital will decrease the level or outcome of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. pentobarbital will decrease the level or influence of fentanyl by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead to some lessen in fentanyl plas... https://johnm371hln8.dgbloggers.com/profile