Pentobarbital will lower the extent or effect of meloxicam by impacting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the extent or impact of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will lessen the level or impact of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4... https://barrettj396tuu4.blogunteer.com/profile