TL;DR: The use of brown alga (Bifurcaria bifurcata) inside the biosynthesis of copper oxide nanoparticles of dimensions 5–45 nm is documented for The 1st time and these nanoparticles had been observed to exhibit substantial antibacterial exercise versus two different strains of bacteria. The website is protected. The https:// assures that https://www.directivepublications.org/journal-of-applied-nanoscience/